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BW 755C
CAS No. 66000-40-6
BW 755C( —— )
Catalog No. M27503 CAS No. 66000-40-6
BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 65 | In Stock |
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| 5MG | 56 | In Stock |
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| 10MG | 75 | In Stock |
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| 25MG | 117 | In Stock |
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| 50MG | 164 | In Stock |
|
| 100MG | 239 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBW 755C
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NoteResearch use only, not for human use.
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Brief DescriptionBW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.
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DescriptionBW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways.(In Vitro):BW 755C is approximately equipotent inhibitors of COX-1 and COX-2 in intact cells.
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In Vitro——
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In VivoAnimal Model:Immature Wistar rats ~22 days of age Dosage:0.03, 0.1, 0.3, 1.0, 3.1 and 10 mg/rat Administration:Subcutaneous injection, once Result:Reduced 5-HETE (moderately) and 12-HETE (strongly).
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Synonyms——
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PathwayImmunology/Inflammation
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TargetLipoxygenase
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number66000-40-6
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Formula Weight229.2
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Molecular FormulaC10H10F3N3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (436.30 mM)
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SMILESNC(CC1)=NN1c1cccc(C(F)(F)F)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Chao W, et al. Inotilone from Inonotus linteus suppresses lung cancer metastasis in vitro and in vivo through ROS-mediated PI3K/AKT/MAPK signaling pathways. Sci Rep. 2019 Feb 20;9(1):2344.
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