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SMIP004
CAS No. 143360-00-3
SMIP004( —— )
Catalog No. M26820 CAS No. 143360-00-3
SMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 129 | In Stock |
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| 2MG | 112 | In Stock |
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| 5MG | 174 | In Stock |
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| 10MG | 264 | In Stock |
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| 25MG | 440 | In Stock |
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| 50MG | 620 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameSMIP004
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NoteResearch use only, not for human use.
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Brief DescriptionSMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells.
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DescriptionSMIP004 is an SKP2 E3 ligase inhibitor. SMIP004 is a cancer cell-selective apoptosis inducer of human prostate cancer cells. (In Vitro):SMIP004 reduces the levels of positive cell cycle regulators upregulates cyclin-dependent kinase inhibitors. It also causes G1 arrest, inhibition of colony formation in soft agar, and cell death .(In Vivo):In SCID mice, SMIP004 effectively inhibits the growth of prostate and breast cancer xenografts .
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number143360-00-3
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Formula Weight205.301
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Molecular FormulaC13H19NO
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 100 mg/mL (487.09 mM)
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SMILESCCCCc1ccc(NC(C)=O)c(C)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Xiang J, et al. Synthesis and evaluation of a paclitaxel-binding polymeric micelle for efficient breast cancer therapy. Sci China Life Sci. 2018 Apr;61(4):436-447.
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