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NRC-2694
CAS No. 936446-61-6
NRC-2694( —— )
Catalog No. M26774 CAS No. 936446-61-6
NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 119 | In Stock |
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| 5MG | 107 | In Stock |
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| 10MG | 174 | In Stock |
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| 25MG | 297 | In Stock |
|
| 50MG | 384 | In Stock |
|
| 100MG | 554 | In Stock |
|
| 200MG | 736 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNRC-2694
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NoteResearch use only, not for human use.
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Brief DescriptionNRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.
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DescriptionNRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.(In Vitro):NRC-2694 (80 ng) induce comparable inhibition of EGFR expression.(In Vivo):NRC-2694 (10 mg/kg) regresses the tumor in mice. The maximum tolerated dose of NRC-2694 in male and female mice is 2000 mg/kg (p.o.), in toxicity studies .
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In VitroNRC-2694 at 80 ng (190 nm) concentrations causes comparable inhibition of EGFR expression.
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In VivoIn toxicity studies, the maximum tolerated dose of NRC-2694 in male and female mice is 2000 mg/kg (po). NRC-2694 (10 mg/kg) regresses the tumor in mice.
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Synonyms——
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PathwayAngiogenesis
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TargetEGFR
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RecptorInfluenza virus
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Research Area——
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Indication——
Chemical Information
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CAS Number936446-61-6
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Formula Weight418.497
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Molecular FormulaC24H26N4O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (597.39 mM)
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SMILESCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCCN1CCOCC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.J V Tuttle, et al. Purine 2'-deoxy-2'-fluororibosides as antiinfluenza virus agents. J Med Chem
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