Mibampator

Research use only, not for human use.

Mibampator is an effective and selective AMPA receptor potentiator.

Mibampator is an effective and selective AMPA receptor potentiator.(In Vivo):Mibampator reverses the central effects of an acutely intoxicating dose of ethanol in rats. Mibampator dose-dependently reverses ethanol-induced deficits in both motor coordination and disruptions in an operant task in the food reward test.

——

Incubation of Mibampator (LY451395) with Actinoplanes missouriensis NRRL B3342 generated several metabolites that were previously detected in the in vivo metabolism studies of the preclinical species . LY404187 and Mibampator (LY451395) reverses the central effects of an acutely intoxicating dose of ethanol in the rat. Mibampator (LY451395) significantly and dose-dependently reversed ethanol-induced deficits in both motor coordination and disruptions in an operant task where animals were trained to press a lever for food reward .

LY451395

Membrane Transporter/Ion Channel

iGluR

Human Endogenous Metabolite

——

——

375345-95-2

438.6

C21H30N2O4S2

>98% (HPLC)

In Vitro:?DMSO : ≥ 25 mg/mL (57.00 mM)

CC(C)S(=O)(=O)NC[C@H](C)c1ccc(cc1)-c1ccc(CCNS(C)(=O)=O)cc1

——

(-20℃)

With Ice Pack

≥ 2 years