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AR-C155858
CAS No. 496791-37-8
AR-C155858( —— )
Catalog No. M26608 CAS No. 496791-37-8
AR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 296 | In Stock |
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| 5MG | 282 | In Stock |
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| 10MG | 491 | In Stock |
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| 25MG | 801 | In Stock |
|
| 50MG | 1079 | In Stock |
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| 100MG | 1460 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAR-C155858
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NoteResearch use only, not for human use.
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Brief DescriptionAR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM).
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DescriptionAR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM).(In Vitro):AR-C155858 (10 nM-100 nM) inhibits MCT1/MCT2 C-terminal chimaeras. AR-C155858 inhibits MCT1 expressed in Xenopus oocytes in a time- and concentration-dependent manner. AR-C155858 inhibits MCT2, and the 70% inhibition seen at 10 nM is followed by a gradually increasing inhibition which can only be explained by a Ki value of significantly less than 10 nM.
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In VitroAR-C155858 (10 nM-100 nM) inhibits MCT1/MCT2 C-terminal chimaeras. AR-C155858 inhibits MCT2, and the 70% inhibition seen at 10 nM is followed by a gradually increasing inhibition which can only be explained by a Ki value of significantly less than 10 nM. AR-C155858 inhibits MCT1 expressed in Xenopus oocytes in a time- and concentration-dependent manner.
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In Vivo——
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Synonyms——
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PathwayMembrane Transporter/Ion Channel
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TargetMonocarboxylate Transporter
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RecptorApoptosis| VD/VDR
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Research Area——
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Indication——
Chemical Information
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CAS Number496791-37-8
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Formula Weight461.54
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Molecular FormulaC21H27N5O5S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 70 mg/mL (151.67 mM)
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SMILESCC(C)Cn1c2sc(Cc3c(C)n[nH]c3C)c(C(=O)N3C[C@H](O)CO3)c2c(=O)n(C)c1=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ryoko Okamoto, et al. Inecalcitol, an analog of 1α,25(OH)(2) D(3) , induces growth arrest of androgen-dependent prostate cancer cells. Int J Cancer. 2012 May 15;130(10):2464-73.
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