Cart
sales@molnova.com
AR-C155858
CAS No. 496791-37-8
AR-C155858( —— )
Catalog No. M26608 CAS No. 496791-37-8
AR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 296 | In Stock |
|
| 5MG | 282 | In Stock |
|
| 10MG | 491 | In Stock |
|
| 25MG | 801 | In Stock |
|
| 50MG | 1079 | In Stock |
|
| 100MG | 1460 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAR-C155858
-
NoteResearch use only, not for human use.
-
Brief DescriptionAR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM).
-
DescriptionAR-C155858 is an inhibitor of monocarboxylate transporter MCT1 and MCT2 (Kis: 2.3 nM and 10 nM).(In Vitro):AR-C155858 (10 nM-100 nM) inhibits MCT1/MCT2 C-terminal chimaeras. AR-C155858 inhibits MCT1 expressed in Xenopus oocytes in a time- and concentration-dependent manner. AR-C155858 inhibits MCT2, and the 70% inhibition seen at 10 nM is followed by a gradually increasing inhibition which can only be explained by a Ki value of significantly less than 10 nM.
-
In VitroAR-C155858 (10 nM-100 nM) inhibits MCT1/MCT2 C-terminal chimaeras. AR-C155858 inhibits MCT2, and the 70% inhibition seen at 10 nM is followed by a gradually increasing inhibition which can only be explained by a Ki value of significantly less than 10 nM. AR-C155858 inhibits MCT1 expressed in Xenopus oocytes in a time- and concentration-dependent manner.
-
In Vivo——
-
Synonyms——
-
PathwayMembrane Transporter/Ion Channel
-
TargetMonocarboxylate Transporter
-
RecptorApoptosis| VD/VDR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number496791-37-8
-
Formula Weight461.54
-
Molecular FormulaC21H27N5O5S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 70 mg/mL (151.67 mM)
-
SMILESCC(C)Cn1c2sc(Cc3c(C)n[nH]c3C)c(C(=O)N3C[C@H](O)CO3)c2c(=O)n(C)c1=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Ryoko Okamoto, et al. Inecalcitol, an analog of 1α,25(OH)(2) D(3) , induces growth arrest of androgen-dependent prostate cancer cells. Int J Cancer. 2012 May 15;130(10):2464-73.
molnova catalog
related products
-
MSC-4381
MSC-4381 (MCT4-IN-1) is an orally available and selectively modeled highly potent inhibitor of monocarboxylic acid transporter protein 4 (MCT4/SLC16A3) with potential anticancer and antitumor activity for the study of osteosarcoma.
-
7-(Diethylamino)coum...
7-(Diethylamino)coumarin-3-carboxylic acid(7ACC) selectively affects a single part of the MCT symporter translocation cycle leading to strict inhibition of lactate influx. This singular activity is associated with antitumor effects less prone to resistance and side effects.
-
7ACC2
7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for inhibition of [14C]-lactate influx; new antitumor treatment targeting lactate transport in Y cells.
