Cart
sales@molnova.com
Home - Products - Membrane Transporter/Ion Channel - Monocarboxylate Transporter - 7-(Diethylamino)coumarin-3-carboxylic acid

7-(Diethylamino)coumarin-3-carboxylic acid

CAS No. 50995-74-9

7-(Diethylamino)coumarin-3-carboxylic acid( DEAC | Coumarin D 1421 | D 1421 )

Catalog No. M20458 CAS No. 50995-74-9

7-(Diethylamino)coumarin-3-carboxylic acid(7ACC) selectively affects a single part of the MCT symporter translocation cycle leading to strict inhibition of lactate influx. This singular activity is associated with antitumor effects less prone to resistance and side effects.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 29 In Stock
100MG Get Quote In Stock
200MG 27 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    7-(Diethylamino)coumarin-3-carboxylic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    7-(Diethylamino)coumarin-3-carboxylic acid(7ACC) selectively affects a single part of the MCT symporter translocation cycle leading to strict inhibition of lactate influx. This singular activity is associated with antitumor effects less prone to resistance and side effects.
  • Description
    7-(Diethylamino)coumarin-3-carboxylic acid(7ACC) selectively affects a single part of the MCT symporter translocation cycle leading to strict inhibition of lactate influx. This singular activity is associated with antitumor effects less prone to resistance and side effects.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    DEAC | Coumarin D 1421 | D 1421
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Monocarboxylate Transporter
  • Recptor
    MCT1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    50995-74-9
  • Formula Weight
    261.27
  • Molecular Formula
    C14H15NO4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:32 mg/mL (122.48 mM)
  • SMILES
    CCN(CC)c1ccc2cc(C(O)=O)c(=O)oc2c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Draoui N Schicke O Seront E et al. Antitumor Activity of 7-Aminocarboxycoumarin Derivatives a New Class of Potent Inhibitors of Lactate Influx but Not Efflux[J]. Molecular Cancer Therapeutics 2014 13(6):1410-1418.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • MSC-4381

    MSC-4381 (MCT4-IN-1) is an orally available and selectively modeled highly potent inhibitor of monocarboxylic acid transporter protein 4 (MCT4/SLC16A3) with potential anticancer and antitumor activity for the study of osteosarcoma.

  • AZD0095

    AZD0095 is a selective inhibitor of MCT4?with an IC50 of 1.3 nM.

  • MCT1-IN-3

    MCT1-IN-3 is a monocarboxylate transporter 1 (MCT1) inhibitor, targeting solute carrier (SLC) monocarboxylate transporter 1 (MCT1; SLC16A1) for cancer treatment.

Sign In Join Free