Cart
sales@molnova.com
Arimoclomol
CAS No. 289893-25-0
Arimoclomol( BRX-220 free base )
Catalog No. M26548 CAS No. 289893-25-0
Arimoclomol is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 223 | In Stock |
|
| 5MG | 215 | In Stock |
|
| 10MG | 330 | In Stock |
|
| 25MG | 548 | In Stock |
|
| 50MG | 765 | In Stock |
|
| 100MG | 1014 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameArimoclomol
-
NoteResearch use only, not for human use.
-
Brief DescriptionArimoclomol is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS).
-
DescriptionArimoclomol is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (ALS).(In Vivo):In male Wistar rats, Arimoclomol (20 mg/kg; gavage) protects cholecystokinin-octapeptide (CCK)-induced acute pancreatitis. The pancreatic levels of HSP60 and HSP72 are significantly increased.
-
In Vitro——
-
In VivoArimoclomol (BRX-220; 20 mg/kg; orally administered for 5 d) has a protective effect againstcholecystokinin-octapeptide (CCK)-induced acute pancreatitis. Animal Model:Male Wistar rats weighing 240 to 270 gDosage:20 mg/kg Administration:Administered intragastrically, for 5 daysResult:Had a protective effect against CCK-induced acute pancreatitis.
-
SynonymsBRX-220 free base
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetHSP
-
RecptorAP-1| LOX| NF-κB| Parasite
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number289893-25-0
-
Formula Weight313.78
-
Molecular FormulaC14H20ClN3O3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO[C@@H](CO\N=C(/Cl)c1cccn(=O)c1)CN1CCCCC1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Hadjipavlou-Litina D, et al. Kukoamine A analogs with lipoxygenase inhibitory activity. J Enzyme Inhib Med Chem. 2009 Oct;24(5):1188-93.
molnova catalog
related products
-
TAS-116
TAS-116 is a novel potent, selective, orally available HSP90α/β inhibitor with Ki of 34.7, 21.3, >50,000, and >50,000 nM for HSP90α, HSP90β, GRP94, and TRAP1, respectively.
-
KU675
A novel, second-generation C-terminal Hsp90 inhibitor with Kd of 191 and 726 uM for Hsp90α and Hsp90β, respectively.
-
HSP27 inhibitor J2
HSP27 inhibitor J2 is a small molecule functional inhibitor of Hsp27.
