Cart
sales@molnova.com
KUNG94
CAS No. 2134571-29-0
KUNG94( KUNG-94 | KUNG 94 )
Catalog No. M13400 CAS No. 2134571-29-0
A potent, selective Grp94 inhibitor with IC50 of 8 nM; displays 10-fold selecticity over Hsp90α.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | In Stock |
|
| 50MG | 1782 | In Stock |
|
| 100MG | 2250 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameKUNG94
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent, selective Grp94 inhibitor with IC50 of 8 nM; displays 10-fold selecticity over Hsp90α.
-
DescriptionA potent, selective Grp94 inhibitor with IC50 of 8 nM; displays 10-fold selecticity over Hsp90α; shows antiproliferative activity against RPMI8226 cells with Gi50 of 1.4 uM, reduces LRP6 levels and induces apoptosis.
-
In Vitro——
-
In Vivo——
-
SynonymsKUNG-94 | KUNG 94
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetHSP
-
RecptorHSP
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2134571-29-0
-
Formula Weight363.388
-
Molecular FormulaC22H18FNO3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESFC1=CC=C(CC2=C(O)C=C(O)C(C(N3CC(C=CC=C4)=C4C3)=O)=C2)C=C1
-
Chemical Name(5-(4-fluorobenzyl)-2,4-dihydroxyphenyl)(isoindolin-2-yl)methanone
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Khandelwal A, et al. ACS Med Chem Lett. 2017 Sep 1;8(10):1013-1018.
molnova catalog
related products
-
Momordin Ic
Momordin Ic might represent a potential anticancer activity, by inducing apoptosis through oxidative stress-regulated mitochondrial dysfunction involving the MAPK and PI3K-mediated iNOS and HO-1 pathways.
-
HSF1A
A small molecule human HSF1 (heat shock transcription factor 1) activator.
-
JG-98
JG-98 is an allosteric Hsp70 inhibitor, displays >3-fold more active, greater stability than MKT-077 against the breast cancer cell lines MDA-MB-231 and MCF-7 (EC50 of 0.4 uM and 0.7 uM, respectively).
