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7-Ketolithocholic acid
CAS No. 4651-67-6
7-Ketolithocholic acid( 3α-Hydroxy-7-oxo-5β-cholanic acid )
Catalog No. M26545 CAS No. 4651-67-6
7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 42 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | 28 | In Stock |
|
| 500MG | 38 | In Stock |
|
| 1G | 52 | In Stock |
|
Biological Information
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Product Name7-Ketolithocholic acid
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NoteResearch use only, not for human use.
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Brief Description7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion.
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Description7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion.
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In Vitro——
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In Vivo——
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Synonyms3α-Hydroxy-7-oxo-5β-cholanic acid
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PathwayProteasome/Ubiquitin
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TargetEndogenous Metabolite
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RecptorPRMT5
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Research Area——
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Indication——
Chemical Information
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CAS Number4651-67-6
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Formula Weight390.56
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Molecular FormulaC24H38O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : ≥ 100 mg/mL (256.04 mM)
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SMILESC[C@H](CCC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])C(C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Christopher R. Smith, et al. Abstract LB003: Fragment based discovery of MRTX9768, a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target MTAP/CDKN2A-deleted tumors. Cancer Res 1 July 2021; 81 (13_Supplement): LB003.
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