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4-Hydroxybenzylamine
CAS No. 696-60-6
4-Hydroxybenzylamine( 4-HOBA | 4-(Aminomethyl)phenol | 4-Hydroxybenzylamine )
Catalog No. M27368 CAS No. 696-60-6
4-HOBA is a less reactive isomer of 2-HOBA as well as related compounds in a mouse model of hypertension.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Name4-Hydroxybenzylamine
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NoteResearch use only, not for human use.
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Brief Description4-HOBA is a less reactive isomer of 2-HOBA as well as related compounds in a mouse model of hypertension.
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Description4-HOBA is a less reactive isomer of 2-HOBA as well as related compounds in a mouse model of hypertension.(In Vivo):4-HOBA attenuated the left ventricular (LV) and lung IsoLGs in mice after TAC. 4-HOBA attenuated TAC-induced LV hypertrophy, heart failure, and the increase of lung weight in mice, and also improved TAC-induced LV dysfunction. Moreover, 4-HOBA effectively attenuated LV cardiomyocyte hypertrophy, lung inflammation, lung fibrosis.
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In Vitro——
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In Vivo——
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Synonyms4-HOBA | 4-(Aminomethyl)phenol | 4-Hydroxybenzylamine
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PathwayProteasome/Ubiquitin
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TargetEndogenous Metabolite
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number696-60-6
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Formula Weight123.155
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Molecular FormulaC7H9NO
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (812.02 mM)
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SMILESNCc1ccc(O)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Furukawa T, Sakamoto N, Suzuki M, Kimura M, Nagasawa H, Sakuda S. Precocene II, a Trichothecene Production Inhibitor, Binds to Voltage-Dependent Anion Channel and Increases the Superoxide Level in Mitochondria of Fusarium graminearum. PLoS One. 2015 Aug 6;10(8):e0135031. doi: 10.1371/journal.pone.0135031. eCollection 2015. PubMed PMID: 26248339; PubMed Central PMCID: PMC4527739.
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