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Home - Products - Metabolic Enzyme/Protease - Dehydrogenase - PfDHODH-IN-1

PfDHODH-IN-1

CAS No. 183945-55-3

PfDHODH-IN-1( —— )

Catalog No. M26373 CAS No. 183945-55-3

PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis. PfDHODH-IN-1 has antimalarial activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 93 In Stock
5MG 103 In Stock
10MG 155 In Stock
25MG 312 In Stock
50MG 461 In Stock
100MG 681 In Stock
200MG 918 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    PfDHODH-IN-1
  • Note
    Research use only, not for human use.
  • Brief Description
    PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis. PfDHODH-IN-1 has antimalarial activity.
  • Description
    PfDHODH-IN-1 is an inhibitor of Plasmodium falciparum dihydroorotate dehydrogenase(PfDHODH) which catalyzes the rate-limiting step for DNA and RNA biosynthesis. PfDHODH-IN-1 has antimalarial activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Dehydrogenase
  • Recptor
    APC
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    183945-55-3
  • Formula Weight
    296.249
  • Molecular Formula
    C14H11F3N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (168.78 mM)
  • SMILES
    O\C(C1CC1)=C(\C#N)C(=O)Nc1ccc(cc1)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Bai R L, Pettit G R, Hamel E. Binding of dolastatin 10 to tubulin at a distinct site for peptide antimitotic agents near the exchangeable nucleotide and vinca alkaloid sites. Journal of Biological Chemistry, 1990, 265(28): 17141-17149.
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