Home - Products - Metabolic Enzyme/Protease - Dehydrogenase - DHODH-IN-16

DHODH-IN-16

CAS No. 2511248-11-4

DHODH-IN-16( —— )

Catalog No. M28280 CAS No. 2511248-11-4

DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	259	Get Quote
10MG	413	Get Quote
100MG	Get Quote	Get Quote
200MG	Get Quote	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

DHODH-IN-16
Note

Research use only, not for human use.
Brief Description

DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).
Description

DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).(In Vitro):DHODH-IN-16 inhibited the growth of MOLM-13 cells effectively (IC50 = 0.2 nM) .
In Vitro

DHODH-IN-16 (Example 22) potently inhibits the growth of MOLM-13 cells with an IC50 of 0.2 nM.
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

Dehydrogenase
Recptor

TNF-α
Research Area

——
Indication

——

Chemical Information

CAS Number

2511248-11-4
Formula Weight

436.48
Molecular Formula

C24H25FN4O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (229.11 mM)
SMILES

CCN(C(CO)=NN1c(cc(C(C(C)C)=CN(c2c(C)cccc2)C2=O)c2c2)c2F)C1=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Deng X, et al. Design, Synthesis, and Evaluation of Dihydrobenzo[cd]indole-6-sulfonamide as TNF-α Inhibitors. Front Chem. 2018 Apr 4;6:98.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

Octanoic acid

CPI-613, a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase, disrupts tumor cell mitochondrial metabolism.
Trilostane

Trilostane is an inhibitor of 3 beta-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome.
L-Allylglycine

L-Allylglycine is a potent inhibitor of the synthetic enzyme for GABA, glutamic acid decarboxylase.

Sign In Join Free