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DHODH-IN-16

CAS No. 2511248-11-4

DHODH-IN-16( —— )

Catalog No. M28280 CAS No. 2511248-11-4

DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	180	In Stock
5MG	163	In Stock
100MG	Get Quote	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

DHODH-IN-16
Note

Research use only, not for human use.
Brief Description

DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).
Description

DHODH-IN-16 is an effective inhibitor of dihydroorotate dehydrogenase (DHODH, IC50 = 0.396 nM for human).(In Vitro):DHODH-IN-16 inhibited the growth of MOLM-13 cells effectively (IC50 = 0.2 nM) .
In Vitro

DHODH-IN-16 (Example 22) potently inhibits the growth of MOLM-13 cells with an IC50 of 0.2 nM.
In Vivo

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Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

Dehydrogenase
Recptor

TNF-α
Research Area

——
Indication

——

Chemical Information

CAS Number

2511248-11-4
Formula Weight

436.48
Molecular Formula

C24H25FN4O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (229.11 mM)
SMILES

CCN(C(CO)=NN1c(cc(C(C(C)C)=CN(c2c(C)cccc2)C2=O)c2c2)c2F)C1=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Deng X, et al. Design, Synthesis, and Evaluation of Dihydrobenzo[cd]indole-6-sulfonamide as TNF-α Inhibitors. Front Chem. 2018 Apr 4;6:98.

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