Nebracetam hydrochloride

CAS No. 1177279-49-0

Nebracetam hydrochloride( WEB 1881 FU hydrochloride )

Catalog No. M26327 CAS No. 1177279-49-0

Nebracetam hydrochloride is an agonist nootropic M1-muscarinic. Nebracetam hydrochloride induces a rise of intracellular Ca2+ concentration.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 30 In Stock
5MG 29 In Stock
10MG 44 In Stock
25MG 73 In Stock
50MG 105 In Stock
100MG 155 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Nebracetam hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Nebracetam hydrochloride is an agonist nootropic M1-muscarinic. Nebracetam hydrochloride induces a rise of intracellular Ca2+ concentration.
  • Description
    Nebracetam hydrochloride is an agonist nootropic M1-muscarinic. Nebracetam hydrochloride induces a rise of intracellular Ca2+ concentration. Nebracetam hydrochloride exhibits an EC50 of 1.59 mM for elevating [Ca2+]i.(In Vitro):Nebracetam involves not only cholinergic mechanisms but also involves lymbic and hippocampal noradrenergic mechanisms.
  • In Vitro
    ——
  • In Vivo
    Nebracetam (10 mg/kg, p.o.) involves not only cholinergic mechanisms but also involves lymbic and hippocampal noradrenergic mechanisms. Animal Model:Male Wistar rats weighing 200-250 g.Dosage:10, 20 mg/kg.Administration:P.O. (single dose).Result:Able to correct this scopolamine-induced disruption of spatial cognition.
  • Synonyms
    WEB 1881 FU hydrochloride
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    AChR
  • Recptor
    VHL
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1177279-49-0
  • Formula Weight
    240.73
  • Molecular Formula
    C12H17ClN2O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (415.40 mM)
  • SMILES
    Cl.NCC1CN(Cc2ccccc2)C(=O)C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31.
molnova catalog
related products
  • Metixene hydrochlori...

    Metixene hydrochloride hydrate has potential anticholinergic activity and inhibits the binding of quinine ring benzoate (QNB) to muscarine receptors, with IC50 and Ki values of 55 nM and 15 nM, respectively.

  • Ethyl (triphenylphos...

    Ethyl (triphenylphosphoranylidene) acetate may act as an cholinesterase inhibitor that inhibits AChE and BChE.

  • Atropine methyl brom...

    Atropine methyl bromide, a muscarinic receptor (mAChR) antagonist.