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DFP00173

CAS No. 672286-03-2

DFP00173( —— )

Catalog No. M26152 CAS No. 672286-03-2

DFP00173 is a potent and selective aquaporin 3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with IC50 of ~0.1-0.4 μM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	167	In Stock
5MG	152	In Stock
10MG	238	In Stock
25MG	389	In Stock
50MG	531	In Stock
100MG	747	In Stock
200MG	1014	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

DFP00173
Note

Research use only, not for human use.
Brief Description

DFP00173 is a potent and selective aquaporin 3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with IC50 of ~0.1-0.4 μM.
Description

DFP00173 is a potent and selective aquaporin 3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with IC50 of ~0.1-0.4 μM. Compared with the homologous AQP subtypes AQP7 and AQP9, DFP00173 is selective for AQP3.(In Vitro):DFP00173 inhibits the glycerol permeability of human red blood cells with IC50 of ~0.2 μM.
In Vitro

DFP00173 inhibits the glycerol permeability of human erythrocytes with an IC50 of ~0.2 μM.
In Vivo

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Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

——
Research Area

——
Indication

——

Chemical Information

CAS Number

672286-03-2
Formula Weight

332.16
Molecular Formula

C11H7Cl2N3O3S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : ≥ 100 mg/mL (301.06 mM)
SMILES

[O-][N+](=O)c1cc(NC(=O)Nc2c(Cl)cccc2Cl)cs1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.S Moein Moghimi, et al. Allergic Reactions and Anaphylaxis to LNP-Based COVID-19 Vaccines. Mol Ther. 2021 Mar 3;29(3):898-900.

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