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Peimine
CAS No. 23496-41-5
Peimine( 5α-Cevane-3β,6α,20-triol | Verticine | Dihydroisoimperialine )
Catalog No. M18278 CAS No. 23496-41-5
Peimine is an inhibitor to inhibit LPS-induced production of inflammatory cytokines by blocking the MAPKs and NF-κB signaling pathway.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 42 | In Stock |
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| 5MG | 38 | In Stock |
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| 10MG | 61 | In Stock |
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| 25MG | 117 | In Stock |
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| 50MG | 184 | In Stock |
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| 100MG | 305 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NamePeimine
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NoteResearch use only, not for human use.
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Brief DescriptionPeimine is an inhibitor to inhibit LPS-induced production of inflammatory cytokines by blocking the MAPKs and NF-κB signaling pathway.
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DescriptionPeimine, also known as Verticine, is a known MAPK inhibitor, as well as an inhibitor of p38, ERK and JNK phosphorylation, and NFκB activation. Peimine shows antitussive, expectorant and anti-inflammatory effects in vivo. Peimine inhibits the growth and motility of prostate cancer cells and induces apoptosis by disruption of intracellular calcium homeostasis through Ca2+ /CaMKII/JNK pathway.
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In Vitro——
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In Vivo——
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Synonyms5α-Cevane-3β,6α,20-triol | Verticine | Dihydroisoimperialine
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaInflammation/Immunology
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Indication——
Chemical Information
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CAS Number23496-41-5
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Formula Weight431.66
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Molecular FormulaC27H45NO3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (115.83 mM)
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SMILESCC1CCC2C(C3CCC4C(C3CN2C1)CC5C4CC(C6C5(CCC(C6)O)C)O)(C)O
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Chemical Name(3S,4aS,5S,6aS,6bS,8aS,9S,9aS,12S,15aR,15bR,16aR,16bS)-9,12,16b-trimethyltetracosahydrobenzo[4,5]indeno[1,2-h]pyrido[1,2-b]isoquinoline-3,5,9-triol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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DPPH
DPPH is a cell-permeable, stable free radical that is commonly used to evaluate the ability of compounds to act as free radical scavengers or hydrogen donors and to measure the antioxidant activity of tissue extractsDPPH shows a strong absorption band at 517nm.
