Cart
sales@molnova.com
Dehydronitrosonisoldipine
CAS No. 87375-91-5
Dehydronitrosonisoldipine( —— )
Catalog No. M26148 CAS No. 87375-91-5
Dehydronitrosonisoldipine is an inhibitor of sterile α and TIR motif-containing 1 and can be used in studies about neurodegenerative disorders.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 245 | Get Quote |
|
| 10MG | 335 | Get Quote |
|
| 25MG | 566 | Get Quote |
|
| 50MG | 806 | Get Quote |
|
| 100MG | 1098 | Get Quote |
|
| 500MG | 2205 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameDehydronitrosonisoldipine
-
NoteResearch use only, not for human use.
-
Brief DescriptionDehydronitrosonisoldipine is an inhibitor of sterile α and TIR motif-containing 1 and can be used in studies about neurodegenerative disorders.
-
DescriptionDehydronitrosonisoldipine is an inhibitor of sterile α and TIR motif-containing 1 and can be used in studies about neurodegenerative disorders. Dehydronitrosonisoldipine inhibits axon degenration and the Vincristine-activated cADPR production in neurons.(In Vitro):Dehydronitrosonisoldipine exhibits an IC50 of 4 μM in the sterile α and TIR motif-containing 1-dN-expression cells, and decreases the cellular cADPR.
-
In VitroDehydronitrosonisoldipine exhibits an IC50 of 4 μM in the SARM1-dN-expression cells, and decreases the cellular cADPR in cells expressing SARM1, but not in expressing SAM-TIR cells.
-
In Vivo——
-
Synonyms——
-
PathwayGPCR/G Protein
-
TargetCalcium Channel
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number87375-91-5
-
Formula Weight370.4
-
Molecular FormulaC20H22N2O5
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (269.98 mM)
-
SMILESCOC(=O)c1c(C)nc(C)c(C(=O)OCC(C)C)c1-c1ccccc1N=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Xu, J., Liu, J., Li, B. et al. Comparison of blood tonic efficacy and chemical constituents of Kadsura interior A.C. Smith and its closely related species. Chin Med 17, 14 (2022). https://doi.org/10.1186/s13020-021-00544-w
molnova catalog
related products
-
Z-944
Z-944 is a potent, highly selective and oral T-type calcium channel blocker with IC50 of 50-160 nM for human Cav3.1, Cav3.2, and Cav3.3 channels.
-
CDN1163
CDN1163 (CDN-1163) is a small molecule, allosteric activator of SERCA2.
-
Ziconotide Acetate ...
Ziconotide is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects.
