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Dehydronitrosonisoldipine

CAS No. 87375-91-5

Dehydronitrosonisoldipine( —— )

Catalog No. M26148 CAS No. 87375-91-5

Dehydronitrosonisoldipine is an inhibitor of sterile α and TIR motif-containing 1 and can be used in studies about neurodegenerative disorders.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 124 In Stock
2MG 69 In Stock
5MG 126 In Stock
10MG 178 In Stock
25MG 306 In Stock
50MG 427 In Stock
100MG 551 In Stock
200MG Get Quote In Stock
500MG 1097 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Dehydronitrosonisoldipine
  • Note
    Research use only, not for human use.
  • Brief Description
    Dehydronitrosonisoldipine is an inhibitor of sterile α and TIR motif-containing 1 and can be used in studies about neurodegenerative disorders.
  • Description
    Dehydronitrosonisoldipine is an inhibitor of sterile α and TIR motif-containing 1 and can be used in studies about neurodegenerative disorders. Dehydronitrosonisoldipine inhibits axon degenration and the Vincristine-activated cADPR production in neurons.(In Vitro):Dehydronitrosonisoldipine exhibits an IC50 of 4 μM in the sterile α and TIR motif-containing 1-dN-expression cells, and decreases the cellular cADPR.
  • In Vitro
    Dehydronitrosonisoldipine exhibits an IC50 of 4 μM in the SARM1-dN-expression cells, and decreases the cellular cADPR in cells expressing SARM1, but not in expressing SAM-TIR cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Calcium Channel
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    87375-91-5
  • Formula Weight
    370.4
  • Molecular Formula
    C20H22N2O5
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (269.98 mM)
  • SMILES
    COC(=O)c1c(C)nc(C)c(C(=O)OCC(C)C)c1-c1ccccc1N=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Xu, J., Liu, J., Li, B. et al. Comparison of blood tonic efficacy and chemical constituents of Kadsura interior A.C. Smith and its closely related species. Chin Med 17, 14 (2022). https://doi.org/10.1186/s13020-021-00544-w
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