Cart
sales@molnova.com
CRAC intermediate 1
CAS No. 1249343-86-9
CRAC intermediate 1( 5-(S)-Fluorowillardiine )
Catalog No. M26129 CAS No. 1249343-86-9
CRAC intermediate 1 is a key intermediate in the chemical synthesis of a series of CRAC channel inhibitors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 10MG | 31 | In Stock |
|
| 25MG | 59 | In Stock |
|
| 50MG | 91 | In Stock |
|
| 100MG | 138 | In Stock |
|
| 200MG | 206 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCRAC intermediate 1
-
NoteResearch use only, not for human use.
-
Brief DescriptionCRAC intermediate 1 is a key intermediate in the chemical synthesis of a series of CRAC channel inhibitors.
-
DescriptionCRAC intermediate 1 is a key intermediate in the chemical synthesis of a series of CRAC channel inhibitors.
-
In Vitro——
-
In Vivo——
-
Synonyms5-(S)-Fluorowillardiine
-
PathwayGPCR/G Protein
-
TargetCalcium Channel
-
RecptorAMPA
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1249343-86-9
-
Formula Weight223.183
-
Molecular FormulaC10H7F2N3O
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : ≥ 50 mg/mL (224.03 mM)
-
SMILESFc1cccc(F)c1C(=O)Nc1cc[nH]n1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
SR33805
SR33805 is a potent antagonist of Ca2+ channel(EC50s of 4.1 nM and 33 nM in depolarized and polarized conditions, respectively)Acute treatment with SR33805 restored the MI-altered cell shortening without affecting the Ca(2+) transient amplitude, suggesting an increase of myofilament Ca(2+) sensitivity in MI myocytes.?
-
Heterophyllin B
Heterophyllin B effectively suppresses the adhesion and invasion of the human esophageal carcinoma cells by mediating the PI3K/AKT/β-catenin pathways.
-
Mibefradil dihydroch...
Mibefradil dihydrochloride is an blocker of calcium channel with moderate selectivity for T-type Ca2+ channels (T-type and L-type currents with IC50s of 2.7 μM and 18.6 μM, respectively). Mibefradil dihydrochloride inhibits reversibly the T- and L-type currents with IC50 values of 2.7 and 18.6 μM, respectively.
