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CAY10595
CAS No. 916047-16-0
CAY10595( —— )
Catalog No. M26090 CAS No. 916047-16-0
CAY10595 is an antagonist of the CRTh2 (DP2) receptor with a Ki of 10 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 189 | In Stock |
|
| 10MG | 332 | In Stock |
|
| 25MG | 439 | In Stock |
|
| 50MG | 642 | In Stock |
|
| 100MG | 865 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCAY10595
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NoteResearch use only, not for human use.
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Brief DescriptionCAY10595 is an antagonist of the CRTh2 (DP2) receptor with a Ki of 10 nM.
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DescriptionCAY10595 is an antagonist of the CRTh2 (DP2) receptor with a Ki of 10 nM.(In Vivo):CAY10595 slightly delays the development of CIA and reduces IgG2a anti-CII levels without modification of the levels of IgG anti-CII.
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In VitroCAY10595 (compound 71) is a potent CRTH2/DP2 receptor antagonist that binds to the human receptor with a Ki of 10 nM.
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In VivoAdministration of the DP2 antagonist CAY10595 slightly delays the development of CIA. Treatment with CAY10595 reduces IgG2a anti-CII levels without modification of IgG anti-CII levels.
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetGPR
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RecptorCK2| MELK| Mps1| NEK6
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Research Area——
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Indication——
Chemical Information
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CAS Number916047-16-0
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Formula Weight451.23
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Molecular FormulaC20H13Cl2FN2O5
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(O)CN1C(=O)C2(C(=O)N(C(=O)C2)CC3=CC(Cl)=CC=C3F)C4=CC(Cl)=CC=C41
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Colombo R, et al. Targeting the mitotic checkpoint for cancer therapy with NMS-P715, an inhibitor of MPS1 kinase. Cancer Res. 2010 Dec 15;70(24):10255-64.
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