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P2Y2R/GPR17 antagonist 1
CAS No. 2395016-49-4
P2Y2R/GPR17 antagonist 1( —— )
Catalog No. M35640 CAS No. 2395016-49-4
P2Y2R/GPR17 antagonist 1 (Compound 14m) is a dual antagonist with an IC50 of 3.17 μM for P2Y2R and 1.67 μM for GPR17.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 43 | In Stock |
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| 5MG | 29 | In Stock |
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| 10MG | 42 | In Stock |
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| 25MG | 85 | In Stock |
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| 50MG | 148 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameP2Y2R/GPR17 antagonist 1
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NoteResearch use only, not for human use.
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Brief DescriptionP2Y2R/GPR17 antagonist 1 (Compound 14m) is a dual antagonist with an IC50 of 3.17 μM for P2Y2R and 1.67 μM for GPR17.
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DescriptionP2Y2R/GPR17 antagonist 1 (Compound 14m) is a dual P2Y2R and GPR17 antagonist with IC50 values of 3.17 μM and 1.67 μM against P2Y2R and GPR17, respectively. P2Y2R/GPR17 antagonist 1 shows excellent metabolic stability in human liver microsomes.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetGPR
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RecptorGPR
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Research Area——
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Indication——
Chemical Information
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CAS Number2395016-49-4
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Formula Weight432.83
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Molecular FormulaC19H13ClN2O6S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (288.80 mM; Ultrasonic )
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SMILES[O-][N+](=O)c1cccc(OS(=O)(=O)c2ccc(NC(=O)c3ccccc3Cl)cc2)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Pillaiyar T, et al. Design, synthesis and biological evaluation of suramin-derived dual antagonists of the proinflammatory G protein-coupled receptors P2Y2 and GPR17. Eur J Med Chem. 2020 Jan 15;186:111789.?
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