Cart
sales@molnova.com
MK2-IN-3
CAS No. 724711-21-1
MK2-IN-3( MK2 Inhibitor III )
Catalog No. M24735 CAS No. 724711-21-1
MK2-IN-3 is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2 or MK-2) and can be used for the treatment of rheumatoid arthritis
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 73 | In Stock |
|
| 5MG | 113 | In Stock |
|
| 10MG | 186 | In Stock |
|
| 25MG | 404 | In Stock |
|
| 50MG | 593 | In Stock |
|
| 100MG | 845 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameMK2-IN-3
-
NoteResearch use only, not for human use.
-
Brief DescriptionMK2-IN-3 is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2 or MK-2) and can be used for the treatment of rheumatoid arthritis
-
DescriptionMK2-IN-3 is a potent, cell-permeable inhibitor of mitogen-activated protein kinase-activated protein kinase 2 (MAPKAP-K2 or MK-2) and can be used for the treatment of rheumatoid arthritis.
-
In Vitro——
-
In Vivo——
-
SynonymsMK2 Inhibitor III
-
PathwayMAPK/ERK Signaling
-
Targetp38 MAPK
-
RecptorMAPK
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number724711-21-1
-
Formula Weight340.38
-
Molecular FormulaC21H16N4O
-
Purity>98% (HPLC)
-
SolubilityDMSO:10 mM
-
SMILESC1CNC(=O)C2=C1NC(=C2)C3=CC(=NC=C3)C4=CC5=CC=CC=C5N=C4
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Gurgis F , kerfeldt, MC, Heng B , et al. Cytotoxic activity of the MK2 inhibitor CMPD1 in glioblastoma cells is independent of MK2[J]. Cell Death Discovery, 2015, 1:15028.
molnova catalog
related products
-
SB 239063
A potent, selective, orally available p38 MAPK inhibitor with IC50 of 44 nM for both p38α and p38β.
-
SM1-71
SM1-71 is a potent multi-targeted acrylamide-modified TAK1 inhibitor that inhibits MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3, SRC, YES1, FGFR1, ZAK (MLTK), MAP3K1, LIMK1 and RSK2.
-
VX-745
A potent and selective p38α kinase inhibitor with IC50 of 9 nM; shows 20-fold selectivity for p38α over p38β (Ki=220 nM) and no significant inhibition for MAP kinases (with the exception of MKK6).
