Cart
sales@molnova.com
CB1 antagonist 2
CAS No. 614726-85-1
CB1 antagonist 2( AM4113 )
Catalog No. M24614 CAS No. 614726-85-1
CB1 antagonist 2 is caimabinoid 1 (CB1) antagonist extracted from patent WO2016184310A1, compound 3. Which inhibits CB1 in vivo with an IC50 of 25.5 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 29 | In Stock |
|
| 5MG | 42 | In Stock |
|
| 10MG | 69 | In Stock |
|
| 25MG | 141 | In Stock |
|
| 50MG | 245 | In Stock |
|
| 100MG | 398 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 900 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCB1 antagonist 2
-
NoteResearch use only, not for human use.
-
Brief DescriptionCB1 antagonist 2 is caimabinoid 1 (CB1) antagonist extracted from patent WO2016184310A1, compound 3. Which inhibits CB1 in vivo with an IC50 of 25.5 nM.
-
DescriptionCB1 antagonist 2 is caimabinoid 1 (CB1) antagonist extracted from patent WO2016184310A1, compound 3. Which inhibits CB1 in vivo with an IC50 of 25.5 nM.
-
In Vitro——
-
In Vivo——
-
SynonymsAM4113
-
PathwayGPCR/G Protein
-
TargetCannabinoid Receptor
-
RecptorCB1
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number614726-85-1
-
Formula Weight380.66
-
Molecular FormulaC17H12Cl3N3O
-
Purity>98% (HPLC)
-
SolubilityDMSO: 60 mg/mL (157.62 mM; Need ultrasonic); H2O: < 0.1 mg/mL (insoluble)
-
SMILESCc1c(-c(cc2)ccc2Cl)n(-c(ccc(Cl)c2)c2Cl)nc1C(N)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Li, S. , et al. "4-methyl-1h-diaryl pyrazole derivatives and their uses as medicament." WO, WO2007121687 A1.
molnova catalog
related products
-
OMDM-5
OMDM-5 is a potent vanilloid receptor type 1 (TRPV1, EC50 = 75 nM) agonist, showing weak ligand activity at cannabinoid type 1 receptor (CB1, Ki=4.9 μM).
-
CB2R/FAAH?modulator-...
CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting CB2R and FAAH, acting as a CB2R agonist (Ki = 10.8 nM) and FAAH inhibitor (IC50 = 6.2 μM), with a Ki value of 152.9 nM for CB1R.
-
Pravadoline
Pravadoline is a cannabinoid receptor agonist. Pravadoline inhibited the PGs synthesis in mouse brain and displayed antinociceptive activity in rodents subjected to a variety of thermal, chemical, and mechanical nociceptive stimuli.
