Conessine

CAS No. 546-06-5

Conessine( Conessinum | Konessin | Neriine | Roquessine | Wrightine )

Catalog No. M24532 CAS No. 546-06-5

Conessine, a steroidal alkaloid isolated from Holarrhena floribunda, interacts with the histamine H3 receptor and has anti-malarial activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 36 In Stock
5MG 57 In Stock
10MG 93 In Stock
25MG 154 In Stock
50MG 221 In Stock
100MG 332 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Conessine
  • Note
    Research use only, not for human use.
  • Brief Description
    Conessine, a steroidal alkaloid isolated from Holarrhena floribunda, interacts with the histamine H3 receptor and has anti-malarial activity.
  • Description
    Conessine, a steroidal alkaloid isolated from Holarrhena floribunda, interacts with the histamine H3 receptor and has anti-malarial activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Conessinum | Konessin | Neriine | Roquessine | Wrightine
  • Pathway
    GPCR/G Protein
  • Target
    Histamine Receptor
  • Recptor
    H3 receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    546-06-5
  • Formula Weight
    356.59
  • Molecular Formula
    C24H40N2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:Soluble
  • SMILES
    CN(C)[C@@H](C1)CC[C@]([C@@H]2CC3)(C)C1=CC[C@H]2[C@H]4CC[C@@H]5[C@]43CN(C)[C@@H]5C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kim H, Lee KI, Jang M, Namkoong S, Park R, Ju H, Choi I, Oh WK, Park J. Conessine Interferes with Oxidative Stress-Induced C2C12 Myoblast Cell Death through Inhibition of Autophagic Flux. PLoS One. 2016 Jun 3;11(6):e0157096. doi: 10.1371/journal.pone.0157096. eCollection 2016. PubMed PMID: 27257813; PubMed Central PMCID: PMC4892631.
molnova catalog
related products
  • PF-03654746

    PF-03654746 (PF 3654746) is a potent, selective, orally bioactive antagonist of H3 receptor with Ki of 2.3 nM.

  • Pitolisant hydrochlo...

    A potent and selective antagonist of H3 receptor with Ki/EC50 of 0.16/1.5 nM.

  • Meclizine dihydrochl...

    Meclizine is a histamine H1 receptor antagonist used to treat nausea and motion sickness, has anti-histamine, anti-muscarinic and anti-oxidative phosphorylation properties.