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Prunin
CAS No. 529-55-5
Prunin( Naringenin 7-0-glucoside )
Catalog No. M24504 CAS No. 529-55-5
Prunin possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can stimulate growth of Pseudomonas aeruginosa and different Bacilllus sp.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 238 | In Stock |
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| 2MG | 151 | In Stock |
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| 5MG | 238 | In Stock |
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| 10MG | 395 | In Stock |
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| 25MG | 594 | In Stock |
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| 50MG | 829 | In Stock |
|
| 100MG | 1144 | In Stock |
|
| 200MG | 1535 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NamePrunin
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NoteResearch use only, not for human use.
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Brief DescriptionPrunin possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can stimulate growth of Pseudomonas aeruginosa and different Bacilllus sp.
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DescriptionPrunin possesses anti-diabetic, and anti-abacterial properties, it can inhibit protein tyrosine phosphatase 1B (PTP1B) and stimulate glucose uptake in insulin-resistant HepG2 cells; it also can stimulate growth of Pseudomonas aeruginosa and different Bacilllus sp. Prunin exhibits a markedly enhanced solubility compared to naringenin and naringin while maintaining the in vitro inhibition of HMG-CoA reductase.
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In VitroPrunin exhibited dose-dependent inhibitory activity against ONOO--mediated tyrosine nitration and stimulated glucose uptake by decreasing PTP1B expression level in insulin-resistant HepG2 cells. Prunin shows significant inhibitory activity against α-glucosidase, with an IC50 of 317 ± 2.12 μM.
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In Vivo——
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SynonymsNaringenin 7-0-glucoside
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PathwayMicrobiology/Virology
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TargetAntifection
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RecptorAnti-infection|Phosphatase
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Research Area——
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Indication——
Chemical Information
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CAS Number529-55-5
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Formula Weight434.4
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Molecular FormulaC21H22O10
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESO=C1C[C@@H](C2=CC=C(O)C=C2)OC3=CC(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO)O4)O)O)O)=CC(O)=C13
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Prunin- and hesperetin glucoside-alkyl (C4-C18) esters interaction with Jurkat cells plasma membrane: consequences on membrane physical properties and antioxidant capacity.Food Chem Toxicol. 2013 May;55:411-23.
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