Aficamten
CAS No. 2364554-48-1
Aficamten( CK-3773274 )
Catalog No. M24076 CAS No. 2364554-48-1
Aficamten is a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 170 | In Stock |
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| 2MG | 93 | In Stock |
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| 5MG | 155 | In Stock |
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| 10MG | 217 | In Stock |
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| 25MG | 432 | In Stock |
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| 50MG | 641 | In Stock |
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| 100MG | 918 | In Stock |
|
| 200MG | 1237 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAficamten
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NoteResearch use only, not for human use.
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Brief DescriptionAficamten is a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy.
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DescriptionAficamten is a Next-Generation Cardiac Myosin Inhibitor for the Treatment of Hypertrophic Cardiomyopathy.
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In Vitro——
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In Vivo——
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SynonymsCK-3773274
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number2364554-48-1
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Formula Weight337.38
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Molecular FormulaC18H19N5O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (370.50 mM)
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SMILESO=C(C1=CN(C)N=C1)N[C@@H]2CCC3=C2C=CC(C4=NOC(CC)=N4)=C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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CJJ300
CJJ300 is a transforming growth factor-β (TGF-β) inhibitor with an IC50 of 5.3 μM, disrupting the TGF-β-TβR-I-TβR-II signaling complex and inhibiting cell migration.
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Ethyl linoleate
Ethyl linoleate is a natural product and can inhibit the expression of inflammatory mediators and the development of atherosclerotic lesions.
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L-Asparaginase
L-Asparaginase (L-?ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment.Asparaginase is an enzyme that is used as a medication. As a medication, L-asparaginase is used to treat acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), and non-Hodgkin's lymphoma. It is given by injection into a vein, muscle, or under the skin.
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