Cart
sales@molnova.com
Home - Products - Others - Other Targets - 1-(4-hydroxybenzyl)-4-methoxypenanthrene-2,7-diol

1-(4-hydroxybenzyl)-4-methoxypenanthrene-2,7-diol

CAS No. 133740-30-4

1-(4-hydroxybenzyl)-4-methoxypenanthrene-2,7-diol( ——— )

Catalog No. M38832 CAS No. 133740-30-4

BChE-IN-11 (compound 10) is a potent, selective and non-competitive BChE (butyrylcholinesterase) inhibitor, with an IC50 of 2.1 μM. BChE-IN-11 can be used for Alzheimer's disease (AD) research.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
25MG 1554 Get Quote
50MG Get Quote Get Quote
100MG Get Quote Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    1-(4-hydroxybenzyl)-4-methoxypenanthrene-2,7-diol
  • Note
    Research use only, not for human use.
  • Brief Description
    BChE-IN-11 (compound 10) is a potent, selective and non-competitive BChE (butyrylcholinesterase) inhibitor, with an IC50 of 2.1 μM. BChE-IN-11 can be used for Alzheimer's disease (AD) research.
  • Description
    BChE-IN-11 (compound 10) is a potent, selective and non-competitive BChE (butyrylcholinesterase) inhibitor, with an IC50 of 2.1 μM. BChE-IN-11 can be used for Alzheimer's disease (AD) research.
  • In Vitro
    BChE-IN-11 (compound 10) shows inhibition activity for BChE and AChE, with inhibition of 96.6 ± 1.2% and 19.1 ± 3.8% at 25 μg/mL, respectively.BChE-IN-11 binds to the active pocket of BChE via multiple hydrogen bonds with His438, Pro285, Gly115 and π–π stacking with Tyr332 and Trp82.
  • In Vivo
    ———
  • Synonyms
    ———
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    BChE: 2.1\u2009±\u20090.3 μM (IC50), AChE
  • Research Area
    ———
  • Indication
    ———

Chemical Information

  • CAS Number
    133740-30-4
  • Formula Weight
    346.38
  • Molecular Formula
    C22H18O4
  • Purity
    >98% (HPLC)
  • Solubility
    ———
  • SMILES
    ———
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Liu Y, et al. Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Bletilla striata as butyrylcholinesterase inhibitors. Sci Rep. 2022 Aug 11;12(1):13649.?
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • N-Acetyl-L-phenylala...

    N-Acetyl-L-phenylalanine is an essential amino acid produced for medical feed and nutritional applications. It appears in large amount in urine of patients with phenylketonuria which is a human genetic disorder due to the lack of phenylalanine hydroxylase the enzyme necessary to metabolize phenylalanine to tyrosine.

  • THIP

    THIP has a strong affinity for the δ subunit of GABAA receptors. THIP is a functionally selective GABAAR ligand, agonistic to α4β1δ, α4β3δ, and weakly antagonistic to αβγ and α4β2δ GABAARs.

  • Laminin (925-933)(TF...

    Laminin (925-933) (TFA) is a peptide derived from residues 925-933 of the Laminin B1 chain that binds to the laminin receptor.

Sign In Join Free