Broparestrol (E)- has antifertility activity and is a potent inhibitor of rodent mammary tumorigenesis.

ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2(IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively)ND-646-an allosteric inhibitor of the ACC enzymes. ACC1 and ACC2 that prevents ACC subunit dimerization-to suppress fatty acid synthesis in vitro and in vivo.?

5-Hydroxyindole, a hydroxylated indole, can be found in a vast array of pharmacologically active agents and natural products. 5-Hydroxyindole slows desensitization of the 5-HT3 receptor-mediated ion current in N1E-115 neuroblastoma cells.