Aucubin( —— )

Catalog No. M18606 CAS No. 479-98-1

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Aucubin
Note

Research use only, not for human use.
Brief Description

Aucubin is an iridoid glycoside with anti-inflammatory, anti-microbial, anti-algesic as well as anti-tumor activities.
Description

Aucubin is an iridoid glycoside. Iridoids are commonly found in plants and function as defensive compounds. Irioids decrease the growth rates of many generalist herbivores. Aucubin was found to protect against liver damage induced by carbon tetrachloride or alpha-amanitin in mice and rats when 80 mg/kg was dosed intraperitoneally.
In Vitro

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In Vivo

Animal Model:Male Wistar rats (200-230 g) induced diabetes by a injection of streptozotocin Dosage:5 mg/kg Administration:I.p. twice daily for the first 5 days, followed by single injections daily for the last 10 days Result: Increased the body weight of streptozotocin-diabetic rats.Lowered the blood glucose level.Decreased the level of lipid peroxidation and increased the activities of antioxidant enzymes.Increased in insulin immunoreactivity and the number of immunoreactive β cells compared with untreated diabetic rats.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

IL-1β| NF-κB
Research Area

Inflammation/Immunology
Indication

——

CAS Number

479-98-1
Formula Weight

346.33
Molecular Formula

C15H22O9
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 31 mg/mL; 89.51 mM
SMILES

C1=CO[C@H]([C@H]2[C@@H]1[C@@H](C=C2CO)O)O[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O
Chemical Name

[1S-(1alpha,4aalpha,5alpha,7aalpha)]-1,4a,5,7a-tetrahydro-5-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-1-yl-beta-D-glucopyranoside

1. Wang SN, et al. Int Immunopharmacol. 2015 Feb;24(2):408-15.

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