Cart
sales@molnova.com
BMS-191095
CAS No. 166095-21-2
BMS-191095( —— )
Catalog No. M23744 CAS No. 166095-21-2
BMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 223 | In Stock |
|
| 5MG | 202 | In Stock |
|
| 10MG | 306 | In Stock |
|
| 25MG | 550 | In Stock |
|
| 50MG | 732 | In Stock |
|
| 100MG | 986 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBMS-191095
-
NoteResearch use only, not for human use.
-
Brief DescriptionBMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.
-
DescriptionBMS-191095 is mitochondrial ATP-sensitive potassium (mitoKATP) channel activator.
-
In Vitro——
-
In VivoAnimal Model:Male Wistar rats with the induction of ischemia induced by middle cerebral artery occlusion (MCAO)Dosage:2.5 or 25 μg Administration:Intraventricular infusion; 30 min/60 min/24 hours before the induction of ischemia, once Result:Reduced total infarct volume in rats with of pretreat dose of 25 mg and 24 h before MCA. Induced a rapid mitochondrial depolarization.
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetPotassium Channel
-
RecptorPotassium Channel
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number166095-21-2
-
Formula Weight408.88
-
Molecular FormulaC22H21ClN4O2
-
Purity>98% (HPLC)
-
SolubilityDMSO:90 mg/mL (220.11 mM)
-
SMILESCC(C)([C@@H]([C@H]1N(Cc2ncc[nH]2)c(cc2)ccc2Cl)O)Oc(cc2)c1cc2C#N
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Katakam PV, et al. Diversity of mitochondria-dependent dilator mechanisms in vascular smooth muscle of cerebral arteries from normal and insulin-resistant rats. Am J Physiol Heart Circ Physiol. 2014 Aug 15;307(4):H493-503.
molnova catalog
related products
-
Tolazamide
Tolazamide is an oral blood glucose lowering drug used for people with Type 2 diabetes.
-
Glyburide
Glibenclamide(Glyburide) is a sulfonylurea compound that modulates insulin production.
-
Senicapoc
A potent, selective Gardos channel blocker that blocks Ca(2+)-induced rubidium flux from human RBCs (IC50=11 nM) and inhibits RBC dehydration (IC50=10-50 nM).
