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Home - Products - Cell Cycle/DNA Damage - Potassium Channel - 2,2,2-Trichloroethanol

2,2,2-Trichloroethanol

CAS No. 115-20-8

2,2,2-Trichloroethanol( —— )

Catalog No. M28141 CAS No. 115-20-8

2,2,2-Trichloroethanol is an agonist of the nonclassical K2P channels TREK-1 and TRAAK.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    2,2,2-Trichloroethanol
  • Note
    Research use only, not for human use.
  • Brief Description
    2,2,2-Trichloroethanol is an agonist of the nonclassical K2P channels TREK-1 and TRAAK.
  • Description
    2,2,2-Trichloroethanol is an agonist of the nonclassical K2P channels TREK-1 and TRAAK.(In Vitro):2,2,2-trichloroethanol dilated the middle cerebral artery and activated the potassium channel in cerebrovascular smooth muscle.
  • In Vitro
    2,2,2-trichloroethanol activates a nonclassical potassium channel in cerebrovascular smooth muscle and dilates the middle cerebral artery.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Potassium Channel
  • Recptor
    5-HT4
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    115-20-8
  • Formula Weight
    149.4
  • Molecular Formula
    C2H3Cl3O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (669.34 mM)
  • SMILES
    OCC(Cl)(Cl)Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Clark RD, et al. Identification of a 5-HT4 receptor antagonist clinical candidate through side-chain modification. Bioorg Med Chem Lett. 2005 Mar 15;15(6):1697-700.
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