Home - Products - Angiogenesis - EGFR - Tyrphostin B44, (+) enantiomer

Tyrphostin B44, (+) enantiomer

CAS No. 133550-37-5

Tyrphostin B44, (+) enantiomer( —— )

Catalog No. M23490 CAS No. 133550-37-5

Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-) enantiomer.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	177	In Stock
10MG	295	In Stock
25MG	502	In Stock
50MG	709	In Stock
100MG	1008	In Stock
500MG	2007	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

Tyrphostin B44, (+) enantiomer
Note

Research use only, not for human use.
Brief Description

Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-) enantiomer.
Description

Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-) enantiomer.
In Vitro

(+)-Tyrphostin B44 (Tyrphostin AG 835) (Compound B50) (0-100 μM) inhibits cell survival with EC50 values of 3.12, 12.5 and 12.5 μM against CALO, INBL and HeLa cells, respectively.
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

EGFR
Recptor

EGFR
Research Area

——
Indication

——

Chemical Information

CAS Number

133550-37-5
Formula Weight

308.33
Molecular Formula

C18H16N2O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : ≥ 100 mg/mL (324.33 mM)
SMILES

C[C@@H](c1ccccc1)NC(/C(/C#N)=C/c(cc1)cc(O)c1O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

PD158780

PD 158780 reversibly inhibits auto and transphosphorylation of all four members of the ErbB receptor superfamily: EGFR ErbB2 ErbB3 and ErbB4 (IC50s: 8μM 49 nM 52 nM and 52 nM in cell assay).
OBX02-011

OBX02-011 is an effective and reversible inhibitor of EGFR tyrosine kinase with IC50s of 0.134 and 2.09 nM for triple mutants Del19/T790M/C797S and L858R/T790M/C797S.
Icotinib

Icotinib is a potent and specific EGFR inhibitor with IC50 of 5 nM.

Sign In Join Free