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Tyrphostin B44, (+) enantiomer

CAS No. 133550-37-5

Tyrphostin B44, (+) enantiomer( —— )

Catalog No. M23490 CAS No. 133550-37-5

Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-) enantiomer.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	79	In Stock
5MG	71	In Stock
10MG	111	In Stock
25MG	193	In Stock
50MG	259	In Stock
100MG	372	In Stock
200MG	505	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Tyrphostin B44, (+) enantiomer
Note

Research use only, not for human use.
Brief Description

Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-) enantiomer.
Description

Tyrphostin B44, (+) enantiomer is an inhibitor of epidermal growth factor receptor (EGFR) kinase with IC50 of 0.86 μM and has less active than the (-) enantiomer.
In Vitro

(+)-Tyrphostin B44 (Tyrphostin AG 835) (Compound B50) (0-100 μM) inhibits cell survival with EC50 values of 3.12, 12.5 and 12.5 μM against CALO, INBL and HeLa cells, respectively.
In Vivo

——
Synonyms

——
Pathway

Angiogenesis
Target

EGFR
Recptor

EGFR
Research Area

——
Indication

——

Chemical Information

CAS Number

133550-37-5
Formula Weight

308.33
Molecular Formula

C18H16N2O3
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : ≥ 100 mg/mL (324.33 mM)
SMILES

C[C@@H](c1ccccc1)NC(/C(/C#N)=C/c(cc1)cc(O)c1O)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

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