m-PEG11-Br
CAS No. 1258596-39-2
m-PEG11-Br( —— )
Catalog No. M23430 CAS No. 1258596-39-2
m-PEG11-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 29 | In Stock |
|
| 50MG | 32 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Namem-PEG11-Br
-
NoteResearch use only, not for human use.
-
Brief Descriptionm-PEG11-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
-
Descriptionm-PEG11-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
-
In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
-
In Vivo——
-
Synonyms——
-
PathwayPROTACs
-
TargetPROTAC
-
RecptorPEGs
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1258596-39-2
-
Formula Weight579.52
-
Molecular FormulaC23H47BrO11
-
Purity>98% (HPLC)
-
SolubilityDMSO:10 mM
-
SMILESCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCBr
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.
molnova catalog
related products
-
Mal-amido-PEG8-NHS e...
Mal-amido-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
-
MS4077
MS4077 is a novel PROTAC (degrader) of ALK, potently decreases cellular levels of oncogenic active ALK fusion proteins in a concentration- and time-dependent manner in SU-DHL-1 lymphoma and NCI-H2228 lung cancer cells (DC50=3 nM).
-
TL13-112
TL13-112 is a novel Anaplastic Lymphoma Kinase (ALK)-PROTAC developed through conjugation of LDK378 and the cereblon ligand pomalidomide.
Cart
sales@molnova.com