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740 Y-P(TFA)
CAS No. ——
740 Y-P(TFA)( 740YPDGFR(TFA),PDGFR 740Y-P(TFA) )
Catalog No. M22770 CAS No. ——
740 Y-P(TFA) is a potent and cell-permeable activator of PI3K.740 Y-P is a synthetic biotinylated peptide.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 312 | In Stock |
|
| 10MG | 521 | In Stock |
|
| 25MG | 670 | In Stock |
|
| 50MG | 1040 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name740 Y-P(TFA)
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NoteResearch use only, not for human use.
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Brief Description740 Y-P(TFA) is a potent and cell-permeable activator of PI3K.740 Y-P is a synthetic biotinylated peptide.
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Description740 Y-P(TFA) is a potent and cell-permeable activator of PI3K.740 Y-P is a synthetic biotinylated peptide. 740 Y-P stimulates mitogenesis at the lowest concentration tested (1 mg/mL). The peptide stimulates mitogenesis in both the presence and absence of serum (0.5%) and in the former instance, a maximal response observed at 50 mg/mL. 740Y-P peptide to stimulate mitogenesis is highly specific and not a general feature of a cell-permeable SH2 domain-binding peptide. 740Y-P is as effective as a growth factor (FGF2) at promoting neuronal cell survival via the established PI 3-kinase-Akt survival cascade. Stimulation of neuronal cell survival by the PDGFR740Y-P peptide is dose-dependent and does not require insulin.
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In Vitro——
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In Vivo——
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Synonyms740YPDGFR(TFA),PDGFR 740Y-P(TFA)
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PathwayPI3K/Akt/mTOR signaling
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TargetPI3K
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RecptorPI3K
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight——
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Molecular Formula——
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Derossi D, et al. Stimulation of mitogenesis by a cell-permeable PI 3-kinase binding peptide. Biochem Biophys Res Commun. 1998 Oct 9;251(1):148-52.
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