IHMT-PI3Kδ-372 S-isomer( —— )

Catalog No. M35371 CAS No. 2429889-61-0

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

IHMT-PI3Kδ-372 S-isomer
Note

Research use only, not for human use.
Brief Description

IHMT-PI3Kδ-372 S-isomer is a potent and selective PI3Kδ inhibitor with an IC50 of 14 nM. IHMT-PI3Kδ-372 S-isomer shows high selectivity over other class I PI3Ks (56～83 fold) and other protein kinases.
Description

IHMT-PI3Kδ-372 S-isomer is a potent and selective PI3Kδ inhibitor with an IC50 of 14 nM. IHMT-PI3Kδ-372 S-isomer shows high selectivity over other class I PI3Ks (56～83 fold) and other protein kinases. IHMT-PI3Kδ-372 can be uesd for chronic obstructive pulmonary disease (COPD) research.
In Vitro

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In Vivo

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Synonyms

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Pathway

PI3K/Akt/mTOR signaling
Target

PI3K
Recptor

PI3K
Research Area

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Indication

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CAS Number

2429889-61-0
Formula Weight

503.5
Molecular Formula

C26H23F2N7O2
Purity

>98% (HPLC)
Solubility

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SMILES

[C@@H](CC)(N1C=2C(C(=N1)C3=CC(F)=C(OC)C=C3)=C(N)N=CN2)C=4N(C(=O)C=5C(N4)=CC=CC5F)C6CC6
Chemical Name

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