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Naphthazarin

CAS No. 475-38-7

Naphthazarin( DHNQ,5,8-Dihydroxy-1,4-naphthoquinone )

Catalog No. M22399 CAS No. 475-38-7

Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Naphthazarin
  • Note
    Research use only, not for human use.
  • Brief Description
    Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation.
  • Description
    Naphthazarin is effective by various cellular mechanisms including oxidative stress, activation of mitochondrial apoptosis-inducing factor (AIF), depolymerization of microtubules, interference with lysosomal function and p53-dependent p21 activation. It triggers apoptosis and has anti-tumor effects.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    DHNQ,5,8-Dihydroxy-1,4-naphthoquinone
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    475-38-7
  • Formula Weight
    190.15
  • Molecular Formula
    C10H6O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Oc1ccc(O)c2C(=O)C=CC(=O)c12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Omar Aljanadi, et al. Stimulation of Suicidal Erythrocyte Death by Naphthazarin. Basic Clin Pharmacol Toxicol. 2015 Dec;117(6):369-74.
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