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5-Benzylidene-3-ethyl rhodanine
CAS No. 18331-34-5
5-Benzylidene-3-ethyl rhodanine( —— )
Catalog No. M20405 CAS No. 18331-34-5
5-Benzylidene-3-ethyl rhodanine(BTR-1) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 51 | In Stock |
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| 2MG | 29 | In Stock |
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| 5MG | 46 | In Stock |
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| 10MG | 77 | In Stock |
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| 25MG | 140 | In Stock |
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| 50MG | 207 | In Stock |
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| 100MG | 313 | In Stock |
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| 200MG | 458 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name5-Benzylidene-3-ethyl rhodanine
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NoteResearch use only, not for human use.
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Brief Description5-Benzylidene-3-ethyl rhodanine(BTR-1) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.
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Description5-Benzylidene-3-ethyl rhodanine(BTR-1) is an active anti-cancer agent. BTR-1 activates apoptosis and induces cell death.
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In VitroBTR-1 (10, 50, 100, and 250 μM, 5 days) dose-dependently causes cytotoxicity in human leukemic cells, with IC50s of 8 and 6 μM at 48 and 72 h, respectively.Cell Viability AssayCell Line:T-cell leukemic cell lines Concentration:10, 50, 100, and 250 μM Incubation Time:5 days Result:Induced cytotoxicity in human leukemic cells in a dose-dependent manner.
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In Vivo——
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Synonyms——
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PathwayApoptosis
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TargetApoptosis
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RecptorApoptosis
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Research Area——
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Indication——
Chemical Information
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CAS Number18331-34-5
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Formula Weight249.35
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Molecular FormulaC12H11NOS2
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Purity>98% (HPLC)
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SolubilityDMSO:25 mg/mL (100.26 mM)
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SMILESCCN1C(=S)S\C(C1=O)=C/c1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Protein kinase inhib...
Protein kinase inhibitors 1 is a novel inhibitor of HIPK2 with an IC50 of 74 nM and Kd of 9.5 nM.
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Sodium taurochenodeo...
Sodium taurochenodeoxycholate is one of the main bioactive substances of animals' bile acid.?Sodium taurochenodeoxycholate induces apoptosis and shows obvious anti-inflammatory and immune regulation properties. It can increase glucose-induced insulin secretion and stimulate the electrical activity of α2-cells and enhance cytosolic Ca(2+) concentration ([Ca(2+)](c)).
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Galgravin
Galgravin has anti-inflammatory, and neuroprotective effects, it can promote neuronal survival and neurite outgrowth, protect hippocampal neurons against amyloid beta peptide (Abeta25-35)-induced cytotoxicity, and protect against neuronal death from 1-methyl-4-phenylpyridinium ion (MPP+)-induced toxicity in cultured rat hippocampal neurons.
