CL 218872

CAS No. 66548-69-4

CL 218872( —— )

Catalog No. M22192 CAS No. 66548-69-4

CL 218872 is a benzodiazepine agonist displaying selectivity for α1 subunit-containing GABAA receptors (Ki values are 130, 1820, 1530, > 10000, 490 and > 10000 nM for α1, α2, α3, α4, α5 and α6-subunit containing receptors respectively).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
25MG 33 In Stock
50MG 58 In Stock
100MG 96 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    CL 218872
  • Note
    Research use only, not for human use.
  • Brief Description
    CL 218872 is a benzodiazepine agonist displaying selectivity for α1 subunit-containing GABAA receptors (Ki values are 130, 1820, 1530, > 10000, 490 and > 10000 nM for α1, α2, α3, α4, α5 and α6-subunit containing receptors respectively).
  • Description
    CL 218872 is a benzodiazepine agonist displaying selectivity for α1 subunit-containing GABAA receptors (Ki values are 130, 1820, 1530, > 10000, 490 and > 10000 nM for α1, α2, α3, α4, α5 and α6-subunit containing receptors respectively). Orally active anxiolytic and anticonvulsant in vivo.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    GABAA
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    66548-69-4
  • Formula Weight
    278.23
  • Molecular Formula
    C13H9F3N4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:13.9 mg/mL (50 mM; Need ultrasonic)
  • SMILES
    Cc1nnc2ccc(nn12)-c1cccc(c1)C(F)(F)F
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Wang B , Lv K , Liu H , et al. Contribution of the α5 GABAA receptor to the discriminative stimulus effects of propofol in rat[J]. Neuroreport, 2018:347-352.
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