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TUG-469
CAS No. 1236109-67-3
TUG-469( TUG469 | TUG 469 )
Catalog No. M28019 CAS No. 1236109-67-3
TUG-469 is an effective free fatty acid 1 receptor agonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 45 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTUG-469
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NoteResearch use only, not for human use.
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Brief DescriptionTUG-469 is an effective free fatty acid 1 receptor agonist.
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DescriptionTUG-469 is an effective free fatty acid 1 receptor agonist.
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In VitroTUG-469 (0-10 μM) shows efficacy to hFFA1 with a pEC50 value of 7.73.TUG-469 (10 μM) increases the insulin secretion under 10 mM glucose stimulation.TUG-469 (0-100 μM) is >200-fold selective for FFA1 over FFA4 with EC50 values of 19 nM and 4.4 μM for FFA1 and FFA4, respectively.TUG-469 (5 μM; 30 min) significantly increases insulin secretion of INS-1 cells with the presence of high glucose concentration (16.7 mM).
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In VivoTUG-469 (5 mg/kg; i.p.; 60 and 90 min after glucose administration) affects blood glucose level. Animal Model:Male NZO mice with glucose administration Dosage:5 mg/kg Administration:Intraperitoneal injection; 5 mg/kg; 60 and 90 min after glucose administration Result:Reduced the blood glucose level.
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SynonymsTUG469 | TUG 469
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PathwayOthers
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TargetOther Targets
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RecptorInfluenza virus|neuroprotection|Antifection
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Research Area——
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Indication——
Chemical Information
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CAS Number1236109-67-3
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Formula Weight345.442
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Molecular FormulaC23H23NO2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (289.49 mM)
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SMILESCc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Jung JW, et al. Isoprenylated flavonoids from the root bark of Morus alba and their hepatoprotective and neuroprotective activities. Arch Pharm Res. 2015 Nov;38(11):2066-75.
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