Cart
sales@molnova.com
ML318
CAS No. 1610516-67-0
ML318( —— )
Catalog No. M22095 CAS No. 1610516-67-0
ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 34 | In Stock |
|
| 5MG | 30 | In Stock |
|
| 10MG | 51 | In Stock |
|
| 25MG | 107 | In Stock |
|
| 50MG | 170 | In Stock |
|
| 100MG | 269 | In Stock |
|
| 200MG | 383 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameML318
-
NoteResearch use only, not for human use.
-
Brief DescriptionML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site).
-
DescriptionML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site). ML318 inhibits P. aeruginosa (PAO1) with IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorPvdQ acylase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1610516-67-0
-
Formula Weight280.22
-
Molecular FormulaC14H8F4N2?
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (356.86 mM)
-
SMILESFc1ccc(cc1)C(C#N)c1cccc(n1)C(F)(F)F
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Jacqueline M Wurst, et al. Identification of inhibitors of PvdQ, an enzyme involved in the synthesis of the siderophore pyoverdine. ACS Chem Biol. 2014 Jul 18;9(7):1536-44.
molnova catalog
related products
-
G-1749
G-1749 does not alter the monomer-dimer equilibrium of IRE, stimulates the RNase activity of unphosphorylated IRE1 and inhibits IRE1-3P, and significantly increases the RNase activity of IRE1-KR-0P.
-
Thalidomide-NH-C6-NH...
Pomalidomide-C6-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based CRBN ligand and linker used in PROTAC technology.
-
N-Acetyl-L-aspartic ...
N-Acetylaspartic acid is a derivative of aspartic acid. It is the second most concentrated molecule in the brain after the amino acid glutamate. It is synthesized in neurons from the amino acid aspartate and acetyl coenzyme A (acetyl CoA).
