ML318( —— )

Catalog No. M22095 CAS No. 1610516-67-0

ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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5MG	110	Get Quote
10MG	178	Get Quote
25MG	403	Get Quote
50MG	592	Get Quote
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Biological Information

Product Name

ML318
Note

Research use only, not for human use.
Brief Description

ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site).
Description

ML318 is a biaryl nitrile PvdQ acylase inhibitor (IC50 of 20 nM for binding in the acyl-binding site). ML318 inhibits P. aeruginosa (PAO1) with IC50 of 19 μM. ML318 prevents pyoverdine production and limits the growth of P. aeruginosa under iron-limiting conditions.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

PvdQ acylase
Research Area

——
Indication

——

Chemical Information

CAS Number

1610516-67-0
Formula Weight

280.22
Molecular Formula

C14H8F4N2?
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (356.86 mM)
SMILES

Fc1ccc(cc1)C(C#N)c1cccc(n1)C(F)(F)F
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Jacqueline M Wurst, et al. Identification of inhibitors of PvdQ, an enzyme involved in the synthesis of the siderophore pyoverdine. ACS Chem Biol. 2014 Jul 18;9(7):1536-44.

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