O-Phosphorylethanolamine

CAS No. 1071-23-4

O-Phosphorylethanolamine( —— )

Catalog No. M19543 CAS No. 1071-23-4

Phosphoethanolamine (PE) is a phosphomonoester metabolite of the phospholipid metabolism. PE is a precursor of phospholipid synthesis and a product of phospholipid breakdown.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1G 26 In Stock

Biological Information

  • Product Name
    O-Phosphorylethanolamine
  • Note
    Research use only, not for human use.
  • Brief Description
    Phosphoethanolamine (PE) is a phosphomonoester metabolite of the phospholipid metabolism. PE is a precursor of phospholipid synthesis and a product of phospholipid breakdown.
  • Description
    Phosphoethanolamine (PE) is a phosphomonoester metabolite of the phospholipid metabolism. PE is a precursor of phospholipid synthesis and a product of phospholipid breakdown. Phosphomonoesters are present at much higher levels in the brain than in other organs. In developing the brain phosphomonoesters are normally elevated during the period of neuritic proliferation. This also coincides with the occurrence of normal programmed cell death and synaptic pruning in developing the brain. These findings are consistent with the role of phosphomonoesters in membrane biosynthesis. PE shows a strong structural similarity to the inhibitory neurotransmitter GABA and the GABAB receptor partial agonist 3-amino-propylphosphonic acid. PE is a phosphomonoester which is decreased in post-mortem Alzheimer's disease (AD) brain.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1071-23-4
  • Formula Weight
    141.06
  • Molecular Formula
    C2H8NO4P
  • Purity
    >98% (HPLC)
  • Solubility
    H2O:250 mg/mL (1772.30 mM; Need ultrasonic)
  • SMILES
    NCCOP(O)(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Klunk W E et al. Inactivity of phosphoethanolamine an endogenous GABA analog decreased in Alzheimer's disease at GABA binding sites[J]. Life Sciences 1995 56(26):2377.
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