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ML401

CAS No. 1597489-14-9

ML401( —— )

Catalog No. M22038 CAS No. 1597489-14-9

ML401 is a selectively EBI2(GPR183) receptor antagonist(IC50 of 1.03 nM) .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 206 In Stock
5MG 187 In Stock
10MG 306 In Stock
25MG 487 In Stock
50MG 641 In Stock
100MG 830 In Stock
200MG 1135 In Stock
500MG Get Quote In Stock
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Biological Information

  • Product Name
    ML401
  • Note
    Research use only, not for human use.
  • Brief Description
    ML401 is a selectively EBI2(GPR183) receptor antagonist(IC50 of 1.03 nM) .
  • Description
    ML401 is a selectively EBI2(GPR183) receptor antagonist(IC50 of 1.03 nM) .
  • In Vitro
    ML401 shows no toxicity (>50 μM) towards immortalized Fa2-N4 human hepatocytes and non-cytotoxic in MTT in both LnCap and IMR-32 cells (>50 μM).
  • In Vivo
    ML401 shows very good stability in both human plasma and mouse plasma.
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    GPR
  • Recptor
    GPR183
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1597489-14-9
  • Formula Weight
    419.74
  • Molecular Formula
    C20H20BrClN2O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mg/mL (23.82 mM; Need ultrasonic)
  • SMILES
    C1CN(CCN1CC2=CC=C(C=C2)Cl)C(=O)C=CC3=CC=C(C=C3)Br
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ardecky R, et al. Functional Antagonists of EBI-2. Probe Reports from the NIH Molecular Libraries Program [Internet].
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