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ML401

CAS No. 1597489-14-9

ML401( —— )

Catalog No. M22038 CAS No. 1597489-14-9

ML401 is a selectively EBI2(GPR183) receptor antagonist(IC50 of 1.03 nM) .

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	206	In Stock
5MG	187	In Stock
10MG	306	In Stock
25MG	487	In Stock
50MG	641	In Stock
100MG	830	In Stock
200MG	1135	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

ML401
Note

Research use only, not for human use.
Brief Description

ML401 is a selectively EBI2(GPR183) receptor antagonist(IC50 of 1.03 nM) .
Description

ML401 is a selectively EBI2(GPR183) receptor antagonist(IC50 of 1.03 nM) .
In Vitro

ML401 shows no toxicity (>50 μM) towards immortalized Fa2-N4 human hepatocytes and non-cytotoxic in MTT in both LnCap and IMR-32 cells (>50 μM).
In Vivo

ML401 shows very good stability in both human plasma and mouse plasma.
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

GPR
Recptor

GPR183
Research Area

——
Indication

——

Chemical Information

CAS Number

1597489-14-9
Formula Weight

419.74
Molecular Formula

C20H20BrClN2O
Purity

>98% (HPLC)
Solubility

DMSO:10 mg/mL (23.82 mM; Need ultrasonic)
SMILES

C1CN(CCN1CC2=CC=C(C=C2)Cl)C(=O)C=CC3=CC=C(C=C3)Br
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Ardecky R, et al. Functional Antagonists of EBI-2. Probe Reports from the NIH Molecular Libraries Program [Internet].

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