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Valrubicin
CAS No. 56124-62-0
Valrubicin( AD-32 )
Catalog No. M21670 CAS No. 56124-62-0
Valrubicin (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 136 | In Stock |
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| 5MG | 85 | In Stock |
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| 10MG | 136 | In Stock |
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| 25MG | 240 | In Stock |
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| 50MG | 361 | In Stock |
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| 100MG | 500 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameValrubicin
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NoteResearch use only, not for human use.
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Brief DescriptionValrubicin (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.
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DescriptionValrubicin (AD 32) inhibits TPA- and PDBu-induced PKC activation (IC50s: 0.85 and 1.25 μM) and has antitumor and anti-inflammatory activity.
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In Vitro——
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In Vivo——
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SynonymsAD-32
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PathwayAngiogenesis
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TargetPKC
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RecptorPKC
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Research AreaCancer
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IndicationBladder cancer
Chemical Information
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CAS Number56124-62-0
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Formula Weight723.64
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Molecular FormulaC34H32F3NO13
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Purity>98% (HPLC)
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SolubilityDMSO: ≥125 mg/mL (172.74 mM);Water: Insoluble
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SMILESCCCCC(OCC([C@]1(O)CC2=C(C(O)=C3C(C4=C(C(C3=C2O)=O)C=CC=C4OC)=O)[C@@H](O[C@]5C[C@](NC(C(F)(F)F)=O)[C@](O)[C@](C)O5)C1)=O)=O
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Chemical Name2-oxo-2-((2S4S)-2512-trihydroxy-4-(((2S4S5S6S)-5-hydroxy-6-methyl-4-(222-trifluoroacetamido)tetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-611-dioxo-1234611-hexahydrotetracen-2-yl)ethyl pentanoate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Chuang LF et al. Activation of human leukemia protein kinase C by tumor promoters and its inhibition by N-trifluoroacetyladriamycin-14-valerate (AD 32). Biochem Pharmacol. 1992 Feb 18;43(4):865-72.
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