Cart
sales@molnova.com
BTZO-1
CAS No. 99420-15-2
BTZO-1( —— )
Catalog No. M21169 CAS No. 99420-15-2
BTZO-1 is an antioxidant response element (ARE) activator with cardioprotective activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 51 | In Stock |
|
| 2MG | 29 | In Stock |
|
| 5MG | 46 | In Stock |
|
| 10MG | 78 | In Stock |
|
| 25MG | 157 | In Stock |
|
| 50MG | 230 | In Stock |
|
| 100MG | 342 | In Stock |
|
| 200MG | 486 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameBTZO-1
-
NoteResearch use only, not for human use.
-
Brief DescriptionBTZO-1 is an antioxidant response element (ARE) activator with cardioprotective activity.
-
DescriptionBTZO-1 is an antioxidant response element (ARE) activator with cardioprotective activity.
-
In VitroBTZO-1 (0-330 nM; 24 hours) dose-dependently suppressed serum deprivation-induced cardiomyocyte death; the minimum effective concentration (MEC1.5),the concentration of a sample necessary to give a 50% increase in cell viability, is 16 nM.BTZO-1 (0.37 μM; 21 hours) upregulates mRNA protein levels of GST Ya and HO-1 in cardiomyocytes.Cell Viability Assay Cell Line:Primary Neonatal Rat Cardiomyocytes Concentration:0-330 nM Incubation Time:24 hours Result:Suppressed serum deprivation or DOX-induced cell death.
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
TargetApoptosis
-
RecptorApoptosis
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number99420-15-2
-
Formula Weight240.29
-
Molecular FormulaC13H8N2OS
-
Purity>98% (HPLC)
-
SolubilityDMSO:8.33 mg/mL (34.67 mM; Need ultrasonic)
-
SMILESO=c1nc(-c2ccccn2)sc2ccccc12
-
Chemical Name2-Pyridin-2-yl-13-benzothiazin-4-one
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Kimura H Sato Y Tajima Y et al. BTZO-1 a Cardioprotective Agent Reveals that Macrophage Migration Inhibitory Factor Regulates ARE-Mediated Gene Expression[J]. Chemistry & Biology 2010 17(12):1282-1294.
molnova catalog
related products
-
FMAU
FMAU (2'-Deoxy-2'-fluoro-5-methyl-beta-D-arabinouridine) is a thymine nucleoside analog with insertional activity on replicating DNA.FMAU can be used to label cells and track DNA synthesis.
-
Gomisin N
Gomisin N isolated from Schisandra chinensis produces beneficial sedative and hypnotic bioactivity. It has the potential for use in the treatment of allergy and inhibits proliferation and induces apoptosis in cancer.
-
Manganese chloride
Manganese chloride inhibits proliferation in a dose- and time-dependent manner induces G0/G1 and S phase arrest and apoptosis in A549 cells.
