Bromelain

Research use only, not for human use.

Bromelain is an anti-inflammatory drug derived from pineapple stem.

Bromelain is an anti-inflammatory drug derived from pineapple stem. It acts through down-regulation of plasma kininogen, degradation of advanced glycation end-product receptors, inhibition of Prostaglandin E2 expression, and regulation of angiogenic biomarkers as well as antioxidant action upstream in the COX-pathway.(In Vivo):Bromelain (40 mg/kg; i.p.; daily; for 7 days; male SD rats) pretreatment reduces the motor dysfunction in the parkinsonian rat model of Parkinson's disease. 6-OHDA injection resulted in a marked motor impairment which is prevented by pretreatment with Bromelain prior to the lesion .

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Animal Model:Male Sprague-Dawley rats injected with 6-OHDA Dosage:40 mg/kg Administration:Intraperitoneal injection; daily; for 7 days Result:Reduced the motor dysfunction in the parkinsonian rat model of parkinson's disease (PD).

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Apoptosis

Apoptosis

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9001-00-7

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>98% (HPLC)

In Vitro:?DMSO : 6.67 mg/mL

CC1OC(OC2C(NC(C)=O)C(O)OC(CO)C2OC2OC(CO)C(OC3OC(COC4OC(CO)C(O)C(O)C4O)C(O)C(O)C3OC3OCC(O)C(O)C3O)C(O)C2NC(C)=O)C(O)C(O)C1O

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(-20℃)

With Ice Pack

≥ 2 years