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2-Chloroadenosine

CAS No. 146-77-0

2-Chloroadenosine( —— )

Catalog No. M20922 CAS No. 146-77-0

2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1 A2A and A3 receptors( Ki:300 80 and 1900 nM respectively).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    2-Chloroadenosine
  • Note
    Research use only, not for human use.
  • Brief Description
    2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1 A2A and A3 receptors( Ki:300 80 and 1900 nM respectively).
  • Description
    2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1 A2A and A3 receptors( Ki:300 80 and 1900 nM respectively).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    AChR
  • Recptor
    Adenosine receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    146-77-0
  • Formula Weight
    301.69
  • Molecular Formula
    C10H12ClN5O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (331.47 mM)
  • SMILES
    Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
  • Chemical Name
    (2R3R4S5R)-2-(6-amino-2-chloro-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-34-diol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Ates N Ilbay G Sahin D . Suppression of generalized seizures activity by intrathalamic 2-chloroadenosine application[J]. Experimental Biology and Medicine 2005 230(7):501-505.
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