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Bisindolylmaleimide IV

CAS No. 119139-23-0

Bisindolylmaleimide IV( —— )

Catalog No. M20912 CAS No. 119139-23-0

Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 59 In Stock
2MG 33 In Stock
5MG 53 In Stock
10MG 86 In Stock
25MG 177 In Stock
50MG 241 In Stock
100MG 338 In Stock
200MG 500 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Bisindolylmaleimide IV
  • Note
    Research use only, not for human use.
  • Brief Description
    Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM).
  • Description
    Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM).
  • In Vitro
    Bisindolylmaleimide IV (Arcyriarubin A) inhibits PKC with an IC50 of 0.1 μM in 1 % DMSO, while the IC50 of 0.55 μM in 10 % DMSO.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    PKC
  • Recptor
    PKC
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    119139-23-0
  • Formula Weight
    327.34
  • Molecular Formula
    C20H13N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (381.87 mM)
  • SMILES
    O=C1NC(=O)C(c2c[nH]c3ccccc23)=C1c1c[nH]c2ccccc12
  • Chemical Name
    34-Bis(1H-indol-3-yl)pyrrole-25-dione

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Toullec D Pianetti P Coste H et al. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C.[J]. Journal of Biological Chemistry 1991 24(24):15771-15781.
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