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Bevirimat
CAS No. 174022-42-5
Bevirimat( PA-457 | MPC-4326 | YK FH312 )
Catalog No. M20655 CAS No. 174022-42-5
Bevirimat(PA-457) is a first-in-class inhibitor of HIV-1 maturation blocking the cleavage of the Gag capsid (CA) precursor CA-SPI to mature CA protein during virion maturation.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 119 | In Stock |
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| 5MG | 92 | In Stock |
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| 10MG | 155 | In Stock |
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| 25MG | 345 | In Stock |
|
| 50MG | 500 | In Stock |
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| 100MG | 714 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBevirimat
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NoteResearch use only, not for human use.
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Brief DescriptionBevirimat(PA-457) is a first-in-class inhibitor of HIV-1 maturation blocking the cleavage of the Gag capsid (CA) precursor CA-SPI to mature CA protein during virion maturation.
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DescriptionBevirimat(PA-457) is a first-in-class inhibitor of HIV-1 maturation blocking the cleavage of the Gag capsid (CA) precursor CA-SPI to mature CA protein during virion maturation.
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In Vitro——
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In Vivo——
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SynonymsPA-457 | MPC-4326 | YK FH312
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PathwayMicrobiology/Virology
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TargetHIV
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RecptorHIV-1
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Research AreaInfection
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IndicationHIV-1 Infection
Chemical Information
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CAS Number174022-42-5
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Formula Weight584.83
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Molecular FormulaC36H56O6
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Purity>98% (HPLC)
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SolubilityDMSO:50 mg/mL (85.49 mM)
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SMILES[H][C@]12[C@@H](CC[C@@]1(CC[C@]1(C)[C@]2([H])CC[C@]2([H])[C@@]3(C)CC[C@H](OC(=O)CC(C)(C)C(O)=O)C(C)(C)[C@]3([H])CC[C@@]12C)C(O)=O)C(C)=C
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Chemical Name(1R3aS5aR5bR7aR9S11aR11bR13aR13bR)-9-((3-carboxy-3-methylbutanoyl)oxy)-5a5b8811a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-3aH-cyclopenta[a]chrysene-3a-carboxylic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Smith P F Ogundele A Forrest A et al. Phase I and II Study of the Safety Virologic Effect and Pharmacokinetics/Pharmacodynamics of Single-Dose 3-O-(3′3′-Dimethylsuccinyl)Betulinic Acid (Bevirimat) against Human Immunodeficiency Virus Infection[J]. Antimicrobial Agents & Chemotherapy 2007 51(10):3574.
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