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XEN-402
CAS No. 1259933-16-8
XEN-402( Funapide | TV-45070 )
Catalog No. M11070 CAS No. 1259933-16-8
XEN-402 (Funapide;TV-45070) is a potent and selective, orally available sodium channel Nav1.7 and Nav1.8 blocker for treatment of pain.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 335 | In Stock |
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| 5MG | 306 | In Stock |
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| 10MG | 464 | In Stock |
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| 25MG | 748 | In Stock |
|
| 50MG | 986 | In Stock |
|
| 100MG | 1330 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameXEN-402
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NoteResearch use only, not for human use.
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Brief DescriptionXEN-402 (Funapide;TV-45070) is a potent and selective, orally available sodium channel Nav1.7 and Nav1.8 blocker for treatment of pain.
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DescriptionXEN-402 (Funapide;TV-45070) is a potent and selective, orally available sodium channel Nav1.7 and Nav1.8 blocker for treatment of pain. Pain Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsFunapide | TV-45070
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PathwayMembrane Transporter/Ion Channel
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TargetSodium Channel
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RecptorSodium Channel
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Research AreaNeurological Disease
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IndicationPain
Chemical Information
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CAS Number1259933-16-8
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Formula Weight429.35
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Molecular FormulaC22H14F3NO5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 200 mg/mL (465.82 mM)
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SMILESO=C([C@]12COC3=C1C=C(OCO4)C4=C3)N(CC5=CC=C(C(F)(F)F)O5)C6=C2C=CC=C6
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Chemical Name(3'S)-1'-{[5-(trifluoromethyl)furan-2-yl]methyl}-2H,6H-spiro[furo[2,3-f][1,3]benzodioxole-7,3'-indol]-2'(1'H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Bagal SK, et al. Bioorg Med Chem Lett. 2014 Aug 15;24(16):3690-9.
2. Goldberg YP, et al. Pain. 2012 Jan;153(1):80-5.
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