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Home - Products - Microbiology/Virology - Antifection - 57-DIMETHOXYFLAVONE

57-DIMETHOXYFLAVONE

CAS No. 21392-57-4

57-DIMETHOXYFLAVONE( —— )

Catalog No. M20412 CAS No. 21392-57-4

57-DIMETHOXYFLAVONE possessed remarkable leishmanicidal potential.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
10MG 32 In Stock
25MG 68 In Stock
50MG 100 In Stock
100MG 165 In Stock
200MG 245 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    57-DIMETHOXYFLAVONE
  • Note
    Research use only, not for human use.
  • Brief Description
    57-DIMETHOXYFLAVONE possessed remarkable leishmanicidal potential.
  • Description
    57-DIMETHOXYFLAVONE possessed remarkable leishmanicidal potential.
  • In Vitro
    Western Blot Analysis Cell Line:B16F10 melanoma cells Concentration:0-25 μM Incubation Time:48 h Result:Induced CREB phosphorylation, and inhibited Akt and GSK-3β phosphorylation.
  • In Vivo
    Animal Model:Aged mice Dosage:25 and 50 mg/kg Administration:p.o.Result:Increased grip strength and the running endurance.Increased muscle volume, weights, and cross-sectional area.Decreased serum and gastrocnemius muscle levels of IL-6 and TNF-α.
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antifection
  • Recptor
    Antifection
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    21392-57-4
  • Formula Weight
    282.29
  • Molecular Formula
    C17H14O4?
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 62.5 mg/mL (221.40 mM)
  • SMILES
    COc1cc(OC)c2c(c1)oc(cc2=O)-c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tasdemir D . Antitrypanosomal and antileishmanial activites of flavoids and their analogues : In vitro in vivo structure-activity relationship and quantitative structure-activity relationship studies[J]. Antimicrob Agents Chemother 2006 50(4):1352-1364.
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