Desmethylbellidifolin

Research use only, not for human use.

Desmethylbellidifolin is a natural xanthone extracted from Gentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity.

Desmethylbellidifolin is a natural xanthone extracted from Gentianella acuta. 1,3,5,8-Tetrahydroxyxanthone has antispasmodic effect and anti-inflammatory activity. Dimethylbellidifolin shows mutagenicity in Salmonella typhimurium TA100, TA98, TA97, and TA2637 by the preincubation method; it also exhibits at the dose of 200 ug/disk a significant inhibition of the growth of Staphylococcus aureus.

1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin) attenuates lipopolysaccharide-induced nitric oxide release and proinflammatory cytokine expression in RAW264.7 cells.

1,3,5,8-Tetrahydroxyxanthone (Desmethylbellidifolin; orally; 5, 10, 20 mg/kg; 12 days) can inhibit trinitrobenzenesulfonic acid (TNBS)-induced ulcerative colitis (UC), reducing inflammatory response and alleviate colon muscle spasm.

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Microbiology/Virology

Antifection

Anti-infection

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2980-32-7

260.2

C13H8O6

>98% (HPLC)

DMSO:10 mM

C1=CC(=C2C(=C1O)C(=O)C3=C(C=C(C=C3O2)O)O)O

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(-20℃)

With Ice Pack

≥ 2 years