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2-Furoic acid

CAS No. 88-14-2

2-Furoic acid( Furan-2-carboxylic acid )

Catalog No. M20299 CAS No. 88-14-2

2-Furoic acid an orally active selective human cathepsin K inhibitor may have the therapeutic potential for the treatment of diseases characterized by excessive bone loss including osteoporosis.Furan-2-carboxylic acid also has anti-bacterial effect.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    2-Furoic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    2-Furoic acid an orally active selective human cathepsin K inhibitor may have the therapeutic potential for the treatment of diseases characterized by excessive bone loss including osteoporosis.Furan-2-carboxylic acid also has anti-bacterial effect.
  • Description
    2-Furoic acid an orally active selective human cathepsin K inhibitor may have the therapeutic potential for the treatment of diseases characterized by excessive bone loss including osteoporosis.Furan-2-carboxylic acid also has anti-bacterial effect.
  • In Vitro
    ——
  • In Vivo
    2-Furoic acid significantly reduces serum cholesterol and serum triglyceride levels. 2-Furoic acid also lowers the liver and small intestine ATP dependent citrate lyase, acetyl CoA synthetase, acyl CoA cholesterol acyl transferase, sn-glycerol 3-phosphate acyl transferase, phosphatidylate phosphohydrolase and heparin induced lipoprotein lipase activities.2-Furoic acid shows the LD50 of 250 mg/kg i.p. in the acute toxicity studies in mice.
  • Synonyms
    Furan-2-carboxylic acid
  • Pathway
    Microbiology/Virology
  • Target
    Antifection
  • Recptor
    Antifection
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    88-14-2
  • Formula Weight
    112.08
  • Molecular Formula
    C5H4O3?
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:100 mg/mL?(892.22 mM)
  • SMILES
    OC(=O)c1ccco1
  • Chemical Name
    2-Furancarboxylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hara S Isoda R Tahvanainen T et al. Trace Amounts of Furan-2-Carboxylic Acids Determine the Quality of Solid Agar Plates for Bacterial Culture[J]. Plos One 2012 7(7):e41142.
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